Lipooligosaccharide of Campylobacter jejuni

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منابع مشابه

Title: Genetic and chemical differentiation of Campylobacter coli and Campylobacter jejuni lipooligosaccharide pathways Running title: Campylobacter coli LOS

1Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki, Agnes Sjöbergin katu 2, Helsinki, FI-00014, Finland. 2College of Medicine, Institute of Life Science, Swansea University, Singleton Park, Swansea SA2 8PP, United Kingdom. 3Institute for Biological Sciences, National Research Council, Ottawa, Ontario K1A 0R6, Canada. 4Department of Biolo...

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Lipooligosaccharide locus class of Campylobacter jejuni: sialylation is not needed for invasive infection

Campylobacter jejuni is a highly diverse enteropathogen that is commonly detected worldwide. It can sometimes cause bacteraemia, but the bacterial characteristics facilitating bloodstream infection are not known. A total of 73 C. jejuni isolates, consecutively collected from blood-borne infections during a 10-year period all over Finland and for which detailed clinical information of the patien...

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Structural characterization of Campylobacter jejuni lipooligosaccharide outer cores associated with Guillain-Barre and Miller Fisher syndromes.

Molecular mimicry between lipooligosaccharides (LOS) of Campylobacter jejuni and gangliosides in peripheral nerves plays a crucial role in the pathogenesis of C. jejuni-related Guillain-Barré syndrome (GBS). We have analyzed the LOS outer core structures of 26 C. jejuni strains associated with GBS and its variant, Miller Fisher syndrome (MFS), by capillary electrophoresis coupled with electrosp...

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The lipooligosaccharide of Campylobacter jejuni: Similarity with multiple types of mammalian glycans beyond gangliosides

R. Scott Houliston, Evgeny Vinogradov, Monika Dzieciatkowska, Jianjun Li, Frank St. Michael, Marie-France Karwaski, Denis Brochu, Harold C. Jarrell, Craig T. Parker, Nobuhiro Yuki, Robert E. Mandrell and Michel Gilbert From the Institute for Biological Sciences, National Research Council Canada, Ottawa, Ontario K1A 0R6 Canada, and the United States Department of Agriculture, Agriculture Researc...

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A link between the assembly of flagella and lipooligosaccharide of the Gram-negative bacterium Campylobacter jejuni.

Campylobacter jejuni is the leading cause of acute bacterial diarrhea worldwide and is implicated in development of Guillain-Barré syndrome. Two major surface features, the outer membrane lipooligosaccharide and flagella, are highly variable and are often targets for modification. Presumably, these modifications provide a competitive advantage to the bacterium. In this work, we identify a gene ...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 2011

ISSN: 0021-9258

DOI: 10.1074/jbc.m110.181750